You will choose your dating preferences based on answering a question from Vanessa at the beginning of the story. You can choose to date men, women, or both. Once you make that decision you cannot change it during the story. No matter your choice, you will have time in the pods with all four potential love interests, 2 men and 2 women. That time with the gender you are not interested in romancing is considered a "friend dates" where you just get to know the other person on a platonic level.